Guarana (Paullinia cupana) is a climbing shrub native to the Amazon basin, valued for its seeds, which contain one of the highest natural concentrations of caffeine of any plant.
Last reviewed October 3, 2026
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Is Guarana safe to use?
Contains a high concentration of caffeine — often roughly twice the caffeine content of coffee by weight — so it should be used cautiously and in smaller amounts than a typical coffee or tea serving. Not recommended in combination with other caffeine sources without accounting for total intake. Use cautiously or avoid during pregnancy, given caffeine's known risks in high amounts, and if you have anxiety, heart arrhythmia, or high blood pressure. Avoid combining with other stimulants.
This is educational information, not medical advice. See our full Disclaimer before use.
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